ATM

Serine-protein kinase ATM is a protein in humans that is encoded by ATM gene. Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes.

ATM Antibodies

ATM for Homo sapiens (Human)

产品货号 产品名称 种属反应性 应用类型
CSB-PA020042 ATM Antibody Human WB,IHC,ELISA
CSB-PA020043 ATM Antibody Human IHC,ELISA
CSB-PA465029 Phospho-ATM (Ser1981) Antibody Human WB,ELISA
CSB-PA612595 ATM Antibody Human IHC,ELISA
CSB-PA243808 ATM Antibody Human IHC,ELISA
CSB-MA974761 ATM Monoclonal Antibody Human ELISA,IHC
CSB-MA429116 ATM Monoclonal Antibody Human ELISA,IHC
CSB-MA341522 ATM Monoclonal Antibody Human ELISA,IHC
CSB-RA618770A1981phHU Phospho-ATM (S1981) Antibody Human ELISA, IF

ATM cDNA

ATM cDNA for Homo sapiens (Human)

产品货号 产品名称 载体 登录号
CSB-CL618770HU ATM pUC NM_000051.3

ATM cDNA for Sus scrofa (Pig)

产品货号 产品名称 载体 登录号
CSB-CL754283PI ATM pUC NM_001123080.1

ATM cDNA for Mus musculus (Mouse)

产品货号 产品名称 载体 登录号
CSB-CL726793MO Atm pUC NM_007499.2